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Single Pfizer Vaccine Shot May Not Protect Against COVID Variants, Study Warns

Single Pfizer Vaccine Shot May Not Protect Against COVID Variants, Study Warns

A single dose of Pfizer’s Covid-19 vaccine may not be enough to protect against the new variants of Covid-19 now dominant in the U.S., except in people who have already been infected with the virus, according to a study published Friday, as data shows a growing number of Americans are choosing to forgo their second shots. 

Blood samples from people who had received one dose of the Pfizer vaccine and were not previously infected with Covid-19 showed lower levels of immunity against the U.K. and South African variants of the virus than people who had previously been infected and received also one dose, researchers wrote in the journal Science..

Professor Rosemary Boyton, an expert in immunology and respiratory medicine at Imperial College London who co-led the research, said the findings underscore the importance of getting a second dose and the need for people to get vaccinated even if they have been infected in the past.

Though people who have had Covid still need to get the first dose of a vaccine—it acts as a kind of booster shot—the researchers said there does not seem to be any additional benefit to further shots, stopping short of saying a second shot isn’t needed.

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